Genomic Technologies in Clinical Diagnostics: Next Generation Sequencing

Learning Outcome 1

Powerful new technologies have been driving forward immense and exciting changes in clinical practice. The days of peering down the microscope to detect chromosome abnormalities are gone, replaced by chromosome analysis at the genomic level. Invasive Down syndrome tests in pregnancy have made way for the evaluation of fetal DNA in maternal blood. And instead of laborious gene-by-gene targeted sequencing, we can now sequence all of our genes in parallel in a single experiment. The course has been approved for distance-learning continuing professional development (CPD) by the Royal College of Pathologists (RCPath): for 10 CPD credits. Understand and apply genomic sequencing technologies This postgraduate-level course, in combination with Genomic Technologies in Clinical Diagnostics: Molecular Techniques, will help you understand these new and established genetic technologies, and their application to clinical practice. This course focuses on genomic sequencing. By the end, you will be able to: demonstrate an understanding of the molecular principles behind next generation sequencing (NGS) technologies; identify appropriate applications of these technologies to clinical scenarios within both diagnostic and research settings; and evaluate alternative applications of next generation sequencing technologies outside of DNA sequencing, such as RNA seq and ChIP-seq.