Genomic Technologies in Clinical Diagnostics: Molecular Techniques

array comparative genomic hybridisation (array CGH);
karyotyping;
fluorescent in situ hybridisation (FISH);
Southern blotting;
multiplex ligation probe amplification (MLPA);
polymerase chain reaction (PCR) and Sanger sequencing;
quantitative fluorescent PCR (QF-PCR);
single nucleotide polymorphism (SNP) genotyping and genome wide association studies (GWAS);
and the extraction and analysis of cell free fetal DNA, including non-invasive prenatal testing (NIPT).

Through practice exercises each week, you will evaluate which laboratory investigations are most suitable for a given clinical scenario. Both Genomic Technologies in Clinical Diagnostics courses draw on the experience of experts in clinical genetics and education at St George’s, University of London. The two courses will provide you with the teaching component of module 1 of the PGCert in Interpretation and Clinical Application of Genomic Data (PGCert ICAG) from St George’s. To apply for the PGCert ICAG, you must be employed as a genetics trainee within the UK, and hold a national training number (NTN) in clinical genetics. If you upgrade and complete both courses on FutureLearn and earn a Certificate of Achievement for each, you will have completed the teaching component of the module, should you apply to study at St George’s.