The Genetic Code, Mutations, and Translation

Welcome to the in-depth course on Molecular Biology: Translation (Protein Synthesis), tailored specifically for medical students preparing for the USMLE Step 1 exam, drawing from the comprehensive Kaplan study materials. This course immerses you in the intricate processes governing protein synthesis, essential for understanding cellular function and pathology. In this course, you will:1.

**Unlock the Genetic Code:** Delve into the universal genetic code, decoding how nucleotide sequences are translated into amino acids, and its implications in genetic variation and disease. 2. **Explore Mutation:** Understand the various types of mutations affecting protein synthesis, their consequences on protein structure and function, and their clinical implications.

3. **Navigate the Steps of Translation:** Master the sequential steps of translation, from initiation, elongation, to termination, exploring the key molecules and regulatory factors involved. 4.

**Examine Inhibitors of Translation:** Investigate inhibitors of translation, such as antibiotics and toxins, and their mechanisms of action, highlighting their relevance in clinical settings. 5. **Understand Co- and Post-Translational Modifications:** Gain insights into the essential modifications proteins undergo during and after synthesis, including folding, cleavage, glycosylation, and phosphorylation, crucial for their biological activity.